Can prayer change things? Does talking to God have any effect whatsoever on what happens? If we are sick, does asking God to heal us make a difference in whether we get better? If a friend has rejected the Lord, is there any point in pleading for his salvation? These are not just theological questions. Our trust in God is at stake. On one hand, the Bible assures us that the Lord answers prayer. On the other, it teaches that God is the sovereign Lord who knows and rules all things according to his perfect will.